- Robin Cook and Clare short left the Blair government over disagreements about the Iraq invasion.
- Michael Heseltine resigned from Thatcher's government over the Westland Helicopter affair.
- Lee Scott, Mike Croquart and Jenny Wilmott who were all parliamentary aides to different ministers resigned over the rise in tuition fees in 2010.
Btw if you have any more examples for this, please comment as I am a bit short on examples!
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