Chromatography

?

What is separation

  • Simplest Definition: solvent extraction. This is single stepped and is best described using a real life example. 
  • Ditsribution ratio (D) is key to knowing what will happen in the extractions 

D = [Corg] / [Caq]

  • If the number is above 1 the organic phase is favoured and separation has occured
  • After this physical separation must occur as they are still in the same container currently eg through a separating funnel
1 of 2

Solvent/liquid liquid extraction

If the analyte dissolves in water a solvent is added that wont change things (immiscible)

  • The analyte will diffuse across the boundary to reach equilibrium although this can take time
  • If the two phases are mixed (for example via shaking within a column) then this can reduce the time before equilibrium is reached
  • Several small samples rather than one large one can make the process much more efficient
  • These methods are extremely common but they cannot isolate one specific item/molecule very often.
2 of 2

Comments

No comments have yet been made

Similar Chemistry resources:

See all Chemistry resources »See all Inorganic Chemistry resources »