G1 checkpoint, G1 arrest, CyclinD- CDK4/6 inhibition at the restriction point,cyclinE- CDK2 inhibition at the G1-S transition
Intra-S phase checkpoint, DNA replication checkpoint, initiated by stalled replication forks, slight delay in S phase until forks restart and finish replication, these forks can collapse, leading to DSB's (picked up in G2/M)
G2 checkpoint, activated by 10-15 DSB's, provide enough time for DSB's to be repaired by homologous recombination, only occurs in G2
spindle checkpoint, mitotic check point, APC/C promotes anaphase by releasing the sister chromatids
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