Blood transfusion science

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  • Created by: z
  • Created on: 15-03-16 20:14

Donor testing

  • Ab to HIV and PCR
  • Hep B surface antigen and PCR
  • Ab to Hep C and PCR for HCV
  • serologic test
    • syphilis (VDRL)
    • HTVL
  • bacterial testing of platelets
  • based on donor Hx
    • HCMV
    • malaria
    • leishmaniasis
    • Western Nile Virus Abs
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Blood group antigens

  • ABO and Rh D antigens tested
  • abs in transfusion
    • naturally occurring:
      • anti-A or B
      • mostly IgM
    • immune
      • e.g. anti Rh D
      • mostly IgG
      • due to exposure to foreign RBCs (e.g. via pregnancy or transfusion)
  • 15% of pop are RhD negative
    • can used for pos and neg recipients
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