When you exercise you respire more. This is because the muscles need more enery to contract.
When the body cannot supply the cells with the oxygen needed to break down glucose, then it has to carry out anaerobic respiration. this means the energy is released without oxygen. This forms lactic acid and energy:
glucose --------> lactic acid + energy
This doesn't produce as much energy as aerobic respiration but it is useful in emergenicies. The lactic acid produced soaks the muscle cells and prevents muscles from doing their job. This causes fatigue and sometimes cramps.
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