1. AP arrives at synaptic knob of the pre-synpatic neurone.
2. Triggers the Ca2+ v.g.c to open causing Ca2+ to diffuse in.
3. Influx of Ca2+ causes vesicles of ACETYCHOLINE to duse with the presynaptic membane.
4. Via exocytosis, ACETYLCHOLINE is released into the synaptic cleft, which diffuses down the concentration gradient and into the post-synpatic membane.
5. ACETYLCHOLINE binds to its receptors on the Na+ channels causing channels to open and letting the Na+ to diffuse in.
6. Influz of Na+ triggers the AP as normal.
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