Biological therapies for schziophernia

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Antipyschotic medication

Conventional:

  • Basic use of the drugs is to reduce the effects of dopamine which then results in reducded symptoms
  • they are dopmaine antagonists in that they bind to the dopamine receptors but do not stimulate them which results in no schizophernic symptoms
  • they are useful for eilimiating positvie symptoms

Aytpical:

  • also act ont he dopamine system
  • thought to aslo block serotonin receptors too
  • it has veen suggested that these drugs do not involved serotonin but only the dopamine system mainly d2 receptors
  • they temporarily block the d2 receptors and then rapidly re-allow normal dopamine activites
  • this drugs are useful for lower levels of side effects such as tardive dyskinsiea
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Effectiveness and appropraiteness of conevntional

Effectivness

  • Davis et al (1980) found a significant difference in terms of relapse rates between treatment and placeo groups in every study reviewed.
  • demonstarting the threapeutic effectiveness
  • no differrence if you lived in a supportive home only worked if you lived in a hostile environment

Appropriatness

  • 30% of people taking this drug develop tardive dyskinsiea and 75% of these cases are irreverisble
  • when taking medication it reinforces that fact that there is somethign wrong with you, resulting in lack of motivational behaviour
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Effectiveness and appropraiteness of aytpical

Effectiveness

  • superority of these drugs when compared to conventional was only moderate
  • this analysis found that two of the new drugs tested were only slightly better than conentional were as the other two were no better
  • that they are meant to be effective with negative effects only has marginal support
  • two of the aytpical drugs were slighty effective

Appropraitness

  • there is a lower likelihood of developing tardive dyskinesia only 5% develop the condition
  • there are fewer side effects too
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