Biological Explanations of Schizophrenia 3.0 / 5 based on 1 rating ? PsychologySchizophreniaA2/A-levelAQA Created by: l.niCreated on: 16-06-13 15:41 Genetic Factors Gottsman found a 46% concordance rate in children with schizophrenia and schizophrenic parents However, it may just be family conflict that causes schizzophrenia (eg Laing's study) Joseph found twin studies after 2001 had a concordance rate of 40.4% in MZ twins compared to about 7% in DZ twins But, this may be due to environment as MZ twins are treated more similarly than DZ twins Tieman et al - 11% with schizophrenic biological mothers had it too (adoption study) 1 of 4 Biochemical Factors Dopamine Hypothesis - dopamine transmitters fire too easily, abnormally high DZ receptors Support by post-mortems showing high dopamine in schixophrenics However, most of these were taking drugs that affected dopamine PET scans regarding schizophrenia and dopamine are yet to be coninving 2 of 4 Neuroanatomical Factors Tory found that schizophrenic patients had 15% larger brain ventricles Negative symptoms of cognitive disturbances and poorer reactions to antipsychotic drugs But there is huge overlap with the ventricle size of healthy patients and so the reliability is questioned 3 of 4 Synoptic Links nature versus nurture evolutionary psychology - schizophrenia found in remote countries 4 of 4
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