Biological Explanations

the biological explanation of schizophrenia

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genetic = twin

TWIN, FAMILY, ADOPTION studies.

  • TWIN- GOTTESMAN.

Twin Studies show genetic and environmental influences.

Identical twins = more concordant

  • MZ (identical) concordance rate = 48%
  • DZ (non identical) concordance rate = 17%
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= family

GOTTESMAN

SZ runs in families?

closer the relative the greater the risk

  • neither parent - 1% chance
  • 1 parent has it - 16% chance
  • both parents have it - 48% chance
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= adoption

TIENARI

GROUP 1 = 155 SZ women gave children to adoption.

GROUP 2 = 155 non SZ women gave children to adoption.

FOUND = 10.3% developed SZ in group 1

1.1% developed SZ in group 2

so......evidence that SZ runs in families. the more genetically simular = greater the risk.

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