Its hard to establish the cause and effect, does higher levels of dopamine cause schizophrenia or does schizophrenia cause higher levels of dopamine??
In the past post-mortem brain dissections were done however with today's technology using PET scans the levels of dopamine can be shown in a living person, these scans support the link as higher dopamine levels have been found.
Drug Therapies have been found to be successful in treating the Type 1 symptioms (Positive) but not Type 2 symptoms (Negative) therefore making the Dopamine Hypothesis Reductionist as it shows there is other factors involved.
The drug Clozapine has been found to help schizophrenics by effecting the levels of seretonin, this shows that it is not all down to dopamine.
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