Neurotransmitter involved in excitatory effect and pleasure. High levels associated with Sz, low levels associated with Parkinson's.
DA 1: Hyperdopaminergia High levels of DA in the subcortex. Excess of DA receptors in Broca's area - responsible for speech production - may be associated with speech poverty and/or audio hallucinations.
DA 2: Hypodopaminergia Focus on abnormal DA systems in the brain's cortex. Low levels of DA in the prefrontal cortex - responsible for decision making and thinking - associated with the negative symptoms of Sz.
It is possible that both explanations are correct.
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