The Pacinian Corpuscle responds to pressure. It consists of the end of a sensory neurone in the centre of layers of tissue, each seperated by a viscous gel. The sensory neurone of a pacinian corpuscle has stretch-mediated sodium channels in the membrane.
- During its resting state, strech-mediated sodium channels are closed so that sodium ions cannot move through. The corpuscle therfore maintains a resting potential.
- When pressure is applied, the membrane of the neurone is stretched by the layers of tissue causing sodium channels to open, allowing sodium ions to diffuse in.
- The inflix of sodium ions cause a change in the polarity of the neurone, creating a generator potential.
- The stronger the pressure, the greater the generator potential, until it reaches a threshold, when an action potential is triggered.
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