Decrease HR (decreased rate of spontaneous depolarisation, slow conduction in atria and AV node), decreased myocardial contractility, inhibition of RAA system, decreased peripheral resistance
Indications: angina, post-MI, tachycardias, possible HF, pregnancy and diabetes
Contraindications: asthma, COPD, heart block, possibly HF, PVD, hyperlipidaemia and physically active
Effectively combined with diuretics, CCBs (not verapamil), alpha blockers
S/E: bronchospasm, postural hypotension, bradycardia
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