A differentiated cell from the parent can be taken, its nucleus is place in an egg cell which has had its own nucleus removed-an enucleated cell.
the egg then goes through the stages of development using genetic information from the inserted nucleus.
the first animal produced in this way was Dolly the sheep in 1996.
the cell was taken from the mammary gland of a 6-year old ewe, its nucleus transplanted into a cell from a second sheep and the inserted into the uterus of a third sheep, then a fourth to develop.
It was only successful once out of 277 attempts.
- the nucleus from a cell of the parent is removed and place into an ovum without a nucleus by Electro-fussion.
- this is then placed into a uterus to develop into an embryo
- it is then removed and placed into a surrogate embryo to develop into an offspring who is identical to the parent at the time of harvesting, so age etc. will be the same.
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