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Inheritance
2 Cystic fibrosis is an inherited disorder that can seriously affect health.

2 (a) Which one of these is affected by cystic fibrosis?
Draw a ring around your answer.

Blood
Cell Membranes
Kidneys
Nervous system
(1 mark)
2 (b) The diagram shows the inheritance of cystic fibrosis in a…

Page 2

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2 (c) Bob and Carol know that there is a risk that their next baby will have cystic fibrosis.
Embryos can be screened for the allele that produces cystic fibrosis.
Many people support the screening of embryos, but others do not.

2 (c) (i) Suggest one reason why many people…

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4 (b) (i) Which man, A or B, is more likely to be the father of the child?

Use the numbers on the DNA fingerprints to explain your choice.
In your answer you should refer to all four people.
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(3 marks)

4 (b)…

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3 In the 1850s, Gregor Mendel carried out breeding experiments using peas.
(a) The importance of Mendel's work was not recognised until the early 1900s.
Explain why.
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(2 marks)

(b) A student repeated one of Mendel's experiments.
The flow chart shows her procedure.




The diagram shows…

Page 5

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(iii) Seed colour in peas is controlled by a single gene which has two alleles.
Use a genetic diagram to show why this ratio of yellow seeds to green seeds was produced by the
second generation.
Use the symbol A to represent the dominant allele, and a to represent the…

Page 6

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(1 mark)
6 (c) Cystic fibrosis is an inherited disorder in which the person's mucus becomes thick.
6 (c) (i) For this gene, one allele in every 30 in the population is the cystic fibrosis allele.
However, only one person in every 900 has cystic fibrosis.
Explain why.
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6 The diagram shows a family tree in which some individuals have an inherited disorder, which may
cause serious long-term health problems.




6 (a) What proportion of the children of A and B have the disorder?
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(1 mark)
6 (b) Explain the evidence from the diagram which shows that…

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(3 marks)
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5 (a) Mr and Mrs Smith both have a history of cystic fibrosis in their families.
Neither of them has cystic fibrosis.
Mr and Mrs Smith are concerned that they may have a child with cystic fibrosis.
Use a genetic diagram to show how they could…

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