OCR B (Salters) - F334 - Chemistry of Materials - What's in a Medicine?

Revision notes on the WM module of the Chemistry of Materials exam from the OCR B (Salters) course

Link to my notes of "The Steel Story

http://getrevising.co.uk/resources/ocr_b_salters_f334_chemistry_of_materials_the_steel_story

Link to my notes on "The Materials Revolution"

http://getrevising.co.uk/resources/ocr_b_salters_f334_chemistry_of_materials_the_materials_revolution

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  • Created by: Michael
  • Created on: 12-12-12 14:44
Preview of OCR B (Salters) - F334 - Chemistry of Materials - What's in a Medicine?

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SANDOWN BAY ACADEMY
OCR Chemistry B (Salters)
Notes, Task Sheets, Questions and Answers
Michael Chard
This document consists of notes from all kinds of sources, answers to task sheets given out during
lessons (which have not been carried out on paper) and any questions from text books and any
relevant past papers, along with the answers.

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OCR Chemistry B (Salters)
Michael Chard
Table of Contents
What's in a Medicine? (WM) .................................................................................................................. 4
Acids, Bases and Bonding.................................................................................................................... 4
Acids and Bases ............................................................................................................................... 4
Bonding ........................................................................................................................................... 5
Properties........................................................................................................................................ 5
Electron Repulsion Theory and Shapes............................................................................................... 6
Organic Reactions ............................................................................................................................... 8
Homologous Series ......................................................................................................................... 8
Carboxylic Acids and Esters................................................................................................................. 9
Carboxylic Acids .............................................................................................................................. 9
Esters ............................................................................................................................................. 10
Phenols.............................................................................................................................................. 10
Structure and Acidity .................................................................................................................... 10
Testing for Phenol ......................................................................................................................... 12
Salts from Phenols ........................................................................................................................ 12
Phenols with Acyl Chlorides .......................................................................................................... 12
Aldehydes and Ketones.....................................................................................................................…read more

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OCR Chemistry B (Salters)
Michael Chard
Using Accurate Molecular Masses ................................................................................................…read more

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OCR Chemistry B (Salters)
Michael Chard
What's in a Medicine? (WM)
Specification:
A study of medicines (such as aspirin) their development, chemistry, synthesis and illustrating some
of the features of the pharmaceutical industry. The chemical ideas in this module are:
Phenols, carboxylic acids, esters, carbonyl compounds;
Acid­base reactions;
Medicine manufacture and testing;
IR spectroscopy and mass spectroscopy.
Chemical Ideas Topics: 6.4, 6.5, 7.5, 8.1, 13.2, 13.3, 13.4, 13.5, 13.7, 15.…read more

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OCR Chemistry B (Salters)
Michael Chard
Bonding
Ionic Bonding and Metals
Ionic bonding is when ions are stuck together by electrostatic attraction.…read more

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OCR Chemistry B (Salters)
Michael Chard
Simple Molecule (covalent)
o Low melting and boiling points
Only have to overcome weak intermolecular bonds ­ not the covalent
bonds)
o Sometimes solid ­ usually liquid or gas
Liquid and gases have the weakest intermolecular bonds
o Solid doesn't conduct electricity
No free electrons to carry the charge
o Liquid doesn't conduct electricity
Same as above
o Solubility depends on how polarized the molecule is
If polar, water can pull apart the molecule (due to the electrostatic
attractions…read more

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OCR Chemistry B (Salters)
Michael Chard
Table of bond angles, shapes and names:
Number Number of Number of
Arrangement
of Bonding Lone Pairs Name of
of Electron Shape of Molecule Bond Angle Examples
Electron Pairs of of Shape
Pairs
Pairs Electrons Electrons
N/A linear 1 N/A linear 180o H2, HCl
2 linear 2 0 linear 180o CO2,
HCN
3 trigonal 3 0 triganol 120o BCl3,
planar planar AlCl3
4 tetrahedral 4 0 tetrahedral 109.5o CH4, SiF4
3 1 trigonal <109.…read more

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OCR Chemistry B (Salters)
Michael Chard
Organic Reactions
Homologous Series
We need to remember the organic compounds from As, the homologous series, their
general formula and how to name them
Alkanes
o General formula
CnH2n+2
o Functional group
N/A (Strictly speaking C-C and C-H bonds are- but they're so unreactive that
they're not normally considered as functional groups)
o Example
2-methylpentane
Alkenes
o General formula
CnH2
o Functional group
C=C
o Example
3-methylbut-1-ene
Alcohols
o General formula
CnH2n+1OGH
o Functional group
O-H
o Example
Butan-1-ol…read more

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OCR Chemistry B (Salters)
Michael Chard
o Functional group
N/A (Strictly speaking C-C and C-H bonds are- but they're so unreactive that
they're not normally considered as functional groups)
o Example
Cyclohexane
Halogenoalkanes
o General formula
-
o Functional group
C-(F,Cl,Br,I)
o Example
1,3-dibromopropane
We also need to be aware of the organic reactions ­ from temperature, reagents,
experimental method etc...
Carboxylic Acids and Esters
Carboxylic Acids
Carboxylic acids contain COOH ­ carboxylic acid functional group.…read more

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OCR Chemistry B (Salters)
Michael Chard
Esters
Alcohols react with carboxylic acids to form esters
o If a carboxylic acid is heated with an alcohol in the presence of an acid catalyst, you
get an ester (usually concentrated sulfuric acid, the spec. also mentions
concentrated hydrochloric acid ­ these are the only two acids that could come up
on the test ­ it supplies H+, but this H+ isn't used to make any products ­ remember
a catalyst is left chemically unchanged).…read more

Comments

Adrianna

Is there a chance you've covered f335 too? 

Michael

Hi Adrianna, sorry I haven't done notes for that module, the best method I found was plenty of past papers and cramming! Not the best method, but worked for me.


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