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Neurochemical and brain structure/function explanations for mood
disorders


Neurochemical explanation

The limbic system plays a significant role in emotion and is linked to other areas of the brain,
such as the endocrine system and autonomic system, via neurotransmitter pathways
When neurotransmitters are in the synaptic cleft ­ only active for…

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anterior cingulated cortex and amygdala. Each of these areas shows a common symptom of
depression, such as memory, mood, body's response to stress and goal related behaviour



Research to support this explanation:

Henrique and Davidson (1990) ­ discovered frontal hypoactivation in a sample of 15 unipolar
depressed patients, and was…

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