Slides in this set
Structure & Formula
C(3032) H(4816) O(872) S(8) Fe(4)
A Tetramer Comprising of 2 Alpha chains, and 2 Beta chains, which make up
its secondary structure (Alpha Helices).
Attached to each chain is a Iron containing molecule known as a Haem group.…read more
Structure of Haem
The Haem group consists of a heterocyclic ring- i.e. a cyclic compound with at least two different elements as
members of the ring, this is known as `Porphyrin'.
The Porphyrin group consists of four pyrrole molecules cyclically linked together. They can be seen in the four
corners of the diagram.…read more
Interactions and Mechanisms
Hb binds with oxygen four times, with each binding, a slight change in
Hb + O2 Hb O2
Hb--O2 + O2 Hb-(O2 )2
Hb-(O2 )2 + O2 Hb-(O2 )3
Hb-(O2 )3 + O2 Hb-(O2 )4…read more
Haemoglobin A - The most common with a normal amount over 95%
Haemoglobin F - Fetal
Haemoglobin C&E - Cause variant forms of haemolytic anemia.
Haemoglobin S - variant form of haemoglobin found in people with
sickle cell disease.…read more