Gas-Liquid Chromatography

Basic explanation of Gas-Liquid Chromatography, sufficient for GCSE Chemistry

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Chemistry HomeworkMeghan Bird10 S/Z
Gas-Liquid Chromatography
What is it used for?
Gas-liquid chromatography is used to separate the compounds in
samples. Along with mass spectrometry, the different compounds in
a substance can be separated and identified. It is often used in
forensic science
What is it?
GLC is very similar to gas chromatography, the only difference being
that the stationary phase is a liquid absorbed by a solid, rather than
a solid alone.
How does it work?
The main stages of GLC:
Sample mixture is vaporised
A gas (typically helium, nitrogen, argon, air) moves the vapour
through the column containing a solid coated in a liquid
Each compound has a different attraction to the liquid/solid in
the column, so will take different amounts of time to pass
through it (retention time)
A detector will record the time and how much of a substance
is passing through, so the number of compounds is shown by
the number of peaks
The compounds can be identified by looking at results for
known substances, if the experiment was performed in the
same conditions

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