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What are enzymes?
1. All enzymes are globular proteins spherical in shape
2. Control biochemical reactions in cells
3. They have the suffix ase
4. Intracellular enzymes are found inside the cell
5. Extracellular enzymes act outside the cell for example digestive
6. Enzymes are catalysts speed up che…

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The shape of the active site changes and moves the substrate closer to
the enzyme
Amino acid

s are moulded into a precise form
Enzyme wraps around substrate to distort it
This lowers the activation energy
An enzymesubstrate complex forms fast reaction
9. Enzyme is not used up in the…

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y Never gonna say goodbye Never gonna tell a lie and hurt you Never gonna give you up Never gonna let you down Never

gonna run around and desert you Never gonna make you cry Never gonna say goodbye Never gonna tell a lie and hurt you Never gonna give…

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Adding mo re
substrate won't yield more product, as no more active
sites are available

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Enzyme Inhibitors

Competetive inhibitors

similar shape to substrate molecule

Bond to the active site of the enzyme but do not react or

alter the chemical struture of the enzyme

High concentration of competetive inhibitors causes a

lower rate of reaction

NonCompetetive inhibitiors

Do not bind to the enzyme's active site…

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collisions more ES complexes
At 042°C rate of reaction is proportional to temp
Enzymes have optimum temp. For their action (usually 37°C in humans)
Above 42°C, enzyme is denatured due to heavy vibration that breaks H
Shape is changed active site can't be used anymore
14. Decreased Temperature


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