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Understanding NICE guidance
Information for people who use NHS services

Naltrexone for managing
opioid dependence
NICE `technology This leaflet is about when naltrexone should be used to treat people who
appraisal guidance' are dependent on opioid drugs (such as heroin and morphine) in the NHS
in England and Wales. It…

Page 2

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This may not be the What has NICE said?
only possible
Naltrexone is recommended as a treatment option for people who
treatment for have been opioid dependent but who have stopped using opioids,
people who are and who are highly motivated to stay free from the drugs in an

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Naltrexone is a drug used to help people stay off opioids altogether
(`abstinence'). It is given after they have stopped taking opioids for at least
7­10 days. It works by blocking the effects of the opioids, so that people
don't get the same result from taking them.

What does…

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More information about opioid dependence
The organisations below can provide more information and support for
people who are dependent on opioids. Please note that NICE is not
responsible for the quality or accuracy of any information or advice
provided by these organisations.
· Addaction, 020 7251 5860
· Adfam,…


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