AS OCR Biology: Mitochondria

AS OCR Biology: Mitochondria

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  • Created by: Hamed
  • Created on: 25-05-11 00:14
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Mitochondria
Mitochondria ­ The site of aerobic respiration:
Glycolysis ­ In the Cytosol
Link Reaction ­ In the Matrix of Mitochondria
Krebs Cycle ­ In the Matrix of Mitochondria
Oxidative Phosphorylation ­ Inner membrane of Mitochondria
The Matrix contains:
Enzymes that catalyze Link Reaction/Krebs cycle
Molecules of coenzyme NAD
Oxaloacetate ­ accepts acetate from Link Reaction
Mitochondrial DNA
Mitochondrial Ribosomes
The Cristae is the inner membrane folded to provide large surface area within the
organelle.
The Outer Membrane contains proteins which form channels or carriers that allow
the passage of molecules such as pyruvate.
The Inner Membrane + Outer Membrane = Envelope
The Inner Membrane:

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Has a different lipid composition to the outer membrane
It is impermeable to most small ions, including H
Is folded into many Cristae for large surface area
Has many Electron carriers and ATP synthase enzymes imbedded.…read more

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Protons flow down
a proton gradient through the ATP synthase, from the intermembrane space into
the matrix. The force of this flow (proton motive force) drives the rotation of part
of the ATP synthase and allows ADP and Pi to join and make ATP. This is
Chemiosmosis.
The coenzyme FAD, involved in the Krebs cycle, is tightly bound to a dehydrogenase
enzyme that is embedded in the inner membrane. The H accepted by the FAD do
not get pumped into the inert membrane space.…read more

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