yes they do (you might have to find quotes yourself, as i don't have the books anymore:
George in some ways is similar to Arthur, for example he takes care of Lennie the same way Arthur takes care of Spider. That Lennie is often described of as an animal supports this point.
Furthermore, the lead characters in both books are strongly affected by women, who in the era of the books did not have a very strong influence in society.
That's all i've got for now, but i'll let you know if i find anymore :) Hope they help