B and T lymphocytes
- 0 votes
I have my textbook but the information on B and T cells is making no sense! What are the key differences and how do they work in immunity and vaccination? Information on memory cells would also be appreciated :) Thanks
- 2 votes
T Lymphocytes mature in the Thymus
B Lymphocytes mature in the Bone marrow.
When T Lymphoctes are activated by antigen, they undergo clonal selection and expansion into T helper cells, T killer cells and T memory cells.
T helper cells stimulate phagocytes and and B plasma cells using cytokines (chemical messengers)
T killer cells destroy cell presenting antigen, flagged up by B plasma cell antibodies.
T memory cells provide immunological memory.
B lymphocytes become activated when come into contact with antigen, they undergo clonal selection and expansion into B plasma cells and B memory cells.
B plasma cells produce and secrete antibodies, which prevent antigen allowing virus to infect anymore cells by either Agglutination or Neutralisation. Also flags them up to T killer so they can be destroyed.
B memory cells stay in blood for immunological memory. This allows a secondary infection to be treated much quicker, as memory cells acan just undergo mitosis and secrete anntibodies faster.
Hope this helps! :)
- 0 votes
Thank you so much! Why can't textbooks be this simple? :P