B and T lymphocytes

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I have my textbook but the information on B and T cells is making no sense! What are the key differences and how do they work in immunity and vaccination? Information on memory cells would also be appreciated :) Thanks

Posted Sat 5th January, 2013 @ 12:23 by Gaby Coghlan

2 Answers

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T Lymphocytes mature in the Thymus

B Lymphocytes mature in the Bone marrow.

When T Lymphoctes are activated by antigen, they undergo clonal selection and expansion into T helper cells, T killer cells and T memory cells. 

T helper cells stimulate phagocytes and and B plasma cells using cytokines (chemical messengers)

T killer cells destroy cell presenting antigen, flagged up by B plasma cell antibodies.

T memory cells provide immunological memory.

B lymphocytes become activated when come into contact with antigen, they undergo clonal selection and expansion into B plasma cells and B memory cells.

B plasma cells produce and secrete antibodies, which prevent antigen allowing virus to infect anymore cells by either Agglutination or Neutralisation. Also flags them up to T killer so they can be destroyed.

B memory cells stay in blood for immunological memory. This allows a secondary infection to be treated much quicker, as memory cells acan just undergo mitosis and secrete anntibodies faster.

Hope this helps! :)

Answered Sat 5th January, 2013 @ 13:45 by Orianne
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Thank you so much! Why can't textbooks be this simple? :P

Answered Sat 5th January, 2013 @ 15:07 by Gaby Coghlan