What is dld and its causes

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  • DLD
    • What is DLD? Developmental Language Disorder (DLD) is proposed to refer to cases of language disorder with no known differentiating condition (as defined above). Distinguishing these cases is important when doing research on aetiology, and is likely also to have implications for prognosis and intervention.” (P1071)“emerges in the course of development, rather than being acquired or associated with a known biomedical cause” (P1071-1072) Bishop et al 2017 
      • distinguishing between DLD and other language disorder •“language disorder’ is proposed for children who are likely to have language problems enduring into middle childhood and beyond, with a significant impact on everyday social interactions or educational progress” (P1070)
        • “Differentiating conditions are biomedical conditions in which language disorder occurs as part of a more complex pattern of impairments. This may indicate a specific intervention pathway. We recommend referring to ‘Language disorder associated with X’, where X is the differentiating condition’” Bishop et al 2017
    • Genetic factors •Runs in families •Between 20% and 63% of children with SLI have a close relative with language impairments •0-19% in control children Leonard 2014•Chromosome 7 point mutation of the FOXP2 Gene•Atypical pattern of inheritance not found in others with SLI •Disagreement about phenotype – Now more commonly  characterised as CAS •Responsible for controlling other genes rather than direct influence on speech and language Lai et al (2001)
      • environmental factors •
      • more genetic factors
    • Co- occurring conditions.. •ADHD •Dyslexia“  Co-occurring disorders are impairments in cognitive, sensori-motor or behavioural domains that can co-occur with DLD and may affect pattern of impairment and response to intervention,  unclear.” causal relation to language problems  (P1072)Bishop et al 2017
    • CAUSES unknown/ unclear but some ideas suggest •Strong genetic influence•Many different sources of genetic influence •Different sources of environmental influence 
      • Genetic factors •Runs in families •Between 20% and 63% of children with SLI have a close relative with language impairments •0-19% in control children Leonard 2014•Chromosome 7 point mutation of the FOXP2 Gene•Atypical pattern of inheritance not found in others with SLI •Disagreement about phenotype – Now more commonly  characterised as CAS •Responsible for controlling other genes rather than direct influence on speech and language Lai et al (2001)
        • environmental factors •
        • more genetic factors

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