TRP channels
- Created by: Ellie0o0o
- Created on: 22-04-15 15:53
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- TRP Receptors
- Super-family of ion channels
- Permeable to cations
- Variable selectivity
- Play a role in response to most external stimuli
- Hetero multimers
- Part of a supramolecular complex
- Hetero multimers
- Present across phyla but not always involved in sensation
- They have a conserved TRP box
- Both intra- and extra- cellular domains can vary
- These can bind to other proteins
- Chanellosome
- These can bind to other proteins
- Could be gated by
- Conformational changes
- Endogenous and exogenous ligands
- Ca2+ levels
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