TRP channels

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  • Created by: Ellie0o0o
  • Created on: 22-04-15 15:53
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  • TRP Receptors
    • Super-family of ion channels
    • Permeable to cations
      • Variable selectivity
    • Play a role in response to most external stimuli
    • Hetero multimers
    • Part of a supramolecular complex
      • Hetero multimers
    • Present across phyla but not always involved in sensation
    • They have a conserved TRP box
    • Both intra- and extra- cellular domains can vary
      • These can bind to other proteins
        • Chanellosome
    • Could be gated by
      • Conformational changes
      • Endogenous and exogenous ligands
      • Ca2+ levels

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