Thrombosis
- Created by: Nadia Morgaine Ullrich
- Created on: 09-10-13 12:05
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- Thrombosis
- it is more likely for a blood clot to form when there are damaged blood vessel walls or when the blood is moving slowly
- how does it happen?
- platelets contact a damaged blood vessel wall and change from flat discs to spheres with long thin projections.
- their cell surfaces change causing them to stick to exposed collegen in the wall and also to each other to form temporary platelet plugs. they also release a substance which activates more platelets.
- the direct contact of blood with collegen within the damages wall also triggers a complex series of chemical reactions
- this cascade of events results in thromboplastin being released
- thromboplastin converts the soluble plasma protein prothrombin into thrombin
- Thrombin is an enzyme which then catalyses the conversion of the plasma protein fibrinogen into insoulbe strands of protein fibrin
- fibrin traps red blood cells and forms a clot. this clot clogs up the artrey making it difficult for blood to get through
- Thrombin is an enzyme which then catalyses the conversion of the plasma protein fibrinogen into insoulbe strands of protein fibrin
- thromboplastin converts the soluble plasma protein prothrombin into thrombin
- this cascade of events results in thromboplastin being released
- the direct contact of blood with collegen within the damages wall also triggers a complex series of chemical reactions
- their cell surfaces change causing them to stick to exposed collegen in the wall and also to each other to form temporary platelet plugs. they also release a substance which activates more platelets.
- platelets contact a damaged blood vessel wall and change from flat discs to spheres with long thin projections.
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