The typical eukaryotic promoter
- Created by: natasha8sherry
- Created on: 10-11-13 15:40
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- The typical eukaryotic promoter
- Requires: core promoter, proximal promoter element, enhancer region
- Enhancers
- Modular enhancers
- position of activator binding site not important
- Dimmer switch - different levels of activation
- Some activity when not all activators bound
- E.g. hunchback gene promoter - binding sites for HB and BCD interchangeable
- Non-modular Enhancers
- Arrangement of activator sites crucial
- On/off switches
- Binding of all activators necessary
- E.g. interferon B enhancer
- Modular enhancers
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