Unit 1; Energy for Life; The importance of ATP

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  • The Importance of ATP
    • ATP's role & characteristics
      • universal energy currency as used in all cells to drive reactions
      • Broken down for muscle movement, biosynthesis, active transport etc.
      • Suited to role as:
        • is inert: doesn't initiate response when introduced to bio tissue
        • can pass out mitochondria to cytoplasm
        • releases energy efficiently
        • releases in usable quantities
        • easily hydrolysed & readily reformed
    • Chemiosmosis
      • flow of protons down electrochemical gradient coupled with ATP synthesis from ADP+Pi
      • in ATP synthesis, electrons & protons have different pathways
        • H atoms transferred from a donor to a recipient along chain, each transfer is REDOX reaction that gives erngy
        • energy from electron transfers pumps H atom protons across membrane creating conc gradient
          • protons flow back down gradient in chemiosmosis through ATPsynthase
    • The proton gradient
      • in light-dep photosynthesis, electrons excited by photons move through ETC
        • energy from transfers pumps protons & creates gradient, leads to chemiosmosis
          • ATP made drives light-indep photo-synthesis.
      • In respiration, electrons are excited by food energy
        • energy released from ETC creates gradient, leads to chemiosmosis
      • Apoptosis: programmed cell death, prevents proton gradient forming & causes death
      • DNP: drug used in weight loss allows ETC but not ATP synthesis, body fatally overheats
    • Electron transport chain (ETC)
      • series of proton carriers on mitochondria & chloroplast inner membrane
      • releases energy in REDOX reactions & incorporates into ATP
      • In respiration, H atoms transferred by dehydrogenase enzymes to coenzymes NAD & FAD
        • NADH brings 2 protons & energy is released to synthesise 3 ATP
          • FADH+ brings and 2 ATP synthesised
      • photosynthesi; photosystems transfer excited electrons to electron acceptors then protein carriers

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