Suitability of Drugs for sustained/controlled release (oral)
- Created by: Popstar
- Created on: 09-04-15 18:31
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- Suitability for oral sustained release
- Dose
- High potency
- Low dose
- Therapeutic Range
- Large
- Solubility/Dissolution Rate
- Not for drug with low sol and high permeability
- Stability in GI tract
- Good
- Absorption rate
- High
- Elimination half-life
- Short ideally
- too long - drug accumulation
- too short - need large dose
- Pre-systemic metabolism
- not desirable
- Dose
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