Substrate - level posphorylation- glycolysis - link reaction - kreb's cycle
- Created by: Sophia Dowden
- Created on: 11-06-16 19:51
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- Substrate - level posphorylation- glycolysis - link reaction - kreb's cycle
- Substrate-level phosphorylation
- 1) Glucose is phosporylated (phosphate comes from ATP)
- 2) The sixth carbon - hexose phospahte - splits into two (lysis splitting of 3C triose phosphate molecules)
- 3) The 3C triose phosphates are dehydrogenated/oxidised and converted into pyruvate
- 4) Energy from the triose phosphate bonds is used to combine ADP + Pi ---> ATP
- Energy budget for glycolysis
- 4 ATPs have been made but 2 have been used, so NET ATP = 2
- 2 Reduced NAD due to reaction
- 2 Pyruvates
- Takes place in the cytoplasm of the cell and does not require oxygen
- Link Reaction
- Occurs in the matrix of the mitochondria and diffuses in as pyruvic acid
- 1) Pyruvate is decarboxylated (removal of CO2) and dehydrogenated (removal of H), hydrogen is picked up/accepted by NAD ---> reduced NAD
- 2) This results in acetate (2C) and this joins with Co enzyme A (2C)
- Energy budget for link reaction
- 2 acetyl co enzyme A (acetyl CoA) goes into the Krebs Cycle
- 2CO2 (is released as waste products)
- 2 Reduced NAD (go to the electron transport chain)
- Krebs Cycle
- Occurs in the matrix
- Energy budget for the Krebs cycle
- 2CO2
- 6NADP
- 2 FADP
- 2ATP
- Substrate-level phosphorylation
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