STI's

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  • STI's
    • problems
      • social stigma
      • problems in later life e.g. cancer
      • infertility
      • congenital infections from mother to child
    • properties
      • infectious agents not spread in large numbers
      • spread through contact
      • sensitive to drying/heat/light
      • can have multiple infections
    • Discharge
      • gonorrhoea
      • chlymydia
      • trichomoniasis
    • Ulcers
      • syphillis
      • chancroid
    • Gonhorroea
      • enters mucous membranes of genital tract
      • uncomplicated infection
        • in men: urethra infection
        • mild vaginitis in women
      • complicated infection
        • men
          • prostatitis
          • epididymus
        • women
          • salpingitus
          • pelvic inflammatory disease
      • neiserria gonorrhoeae
      • presents as scepticaemia or rash
      • found in individuals with immune defiiciencies
      • infected mothers can infect child
        • particularly eyes
      • gram negative diplococci
      • penicillin
      • treatment
        • penicillin resistance higher now
        • doxycycline, treats chlamydia too
        • ceftriaxone
        • cefixime
    • chlamydia
      • complex organisms
      • obligate intracellular parasite
      • growth cycles
        • elementary bodies
          • stable, extracellular
        • reticulate particles
          • intracellular, metabolically active
      • women
        • infertility
        • urethritis
        • increased number of leucytes
      • men
        • non gonnococcal urethritis
        • post gonococcal urethritis
      • majority is asymptomatic
      • chlamydia trachomatis
    • syphilis
      • treponema pallidum
      • painless ulcers
      • systemic illness,low grade fever
      • tertiary syphilis has neurological/cardiovascular signs
      • obligate human pathogen
      • site of primary infection is chancre
      • contains spirochaetes
    • Chancroid
      • haemophilus ducreyi
      • gram negative coccocacillus

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