Specific Immune Response
- Created by: Bhansongal98
- Created on: 27-04-16 15:09
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- Specific Immune Response
- (1) Clonal Selection
- Lymphocytes are produces in the bone marrow
- B-cells reach maturity in the bone marrow
- T cells developed in the thymus
- B lymphocytes are involved in the humoral response (producing antibodies
- Plasma cells circulate the blood and manufacture antibodies
- B memory cells which act as an immunological memory
- T lymphocytes are involved in cell mediated response (combating microorganisms)
- T helper cells release cytokines which trigger proliferation of B cells
- T killer cells attack and kill host-body cells that display the antigen (e.g. virus infected cells)
- T memory cells provide long term immunity by remaining in the blood with the antigen receptor that is complementary to the specific antigen
- T regulator cells stop the immune response and prevent autoimmunity where the body attacks itself
- Lymphocytes are produces in the bone marrow
- (2) Proliferation/ Clonal Expansion
- Cells divide my mitosis to provide more lymphocytes to counteract the antigens
- Correct lymphocytes must be activated
- (3) Differentiation
- The clones of the lymphocytes develop into a range of cells
- B & T memory cells remain in the blood to provide long term immunity
- T killer cells attack infected cells
- T helper cells release interleukins to stimulate proliferation of B cells
- Plasma cells make antibodies
- (1) Clonal Selection
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