Cells and Organelles-Cytosolic chaperones

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  • Created by: jessica
  • Created on: 25-02-13 16:56
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  • Cytosolic chaperones
    • Hsc70 binds to protein, keeping it unfolding (involves ATP hydolysis)
      • Unfolded protein binds to Tom 20/22 receptor
        • Tom20/22 receptor delivers protein to the import pore, Tom40
          • The protein passes through Tom40, then the Tim44 inner membrane pore
            • Matrix Hsc70 assists this process
              • Target sequence is cleaved, Hsc70 released and protein folds

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