Cells and Organelles-Cytosolic chaperones
- Created by: jessica
- Created on: 25-02-13 16:56
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- Cytosolic chaperones
- Hsc70 binds to protein, keeping it unfolding (involves ATP hydolysis)
- Unfolded protein binds to Tom 20/22 receptor
- Tom20/22 receptor delivers protein to the import pore, Tom40
- The protein passes through Tom40, then the Tim44 inner membrane pore
- Matrix Hsc70 assists this process
- Target sequence is cleaved, Hsc70 released and protein folds
- Matrix Hsc70 assists this process
- The protein passes through Tom40, then the Tim44 inner membrane pore
- Tom20/22 receptor delivers protein to the import pore, Tom40
- Unfolded protein binds to Tom 20/22 receptor
- Hsc70 binds to protein, keeping it unfolding (involves ATP hydolysis)
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