Aerobic Respiration
- Created by: Ellie
- Created on: 06-01-14 12:29
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- Respiration
- Glycolysis
- Glycolysis takes place in the cytoplasm of cells
- Glucose is split into two molecules of pyruvate
- Activation of glucose by phosphorylation
- 1.
- Addition of 2 phosphate molecules from ATP being split through hydrolysis
- Each phosphorylated glucose is split into 3- triose phosphate
- 2.
- Oxidation of triose phosphate
- 3.
- Hydrogen is removed and is used to reduce NAD
- Production of ATP
- 4.
- Each triose phosphate is converted to pyruvate
- IN: Glucose, 2xNAD, 2xATP
- OUT: 2x Pyruvate, 2xNADH, 2xATP
- The Link Reaction
- The link reaction takes place in the matrix of the mitochondria. Pyruvates are actively transported in.
- Pyruvate is oxidised by removing hydrogen, to NAD.
- Acetyl group is formed and combines with CoA - acetyl CoA.
- IN: 2x Pyruvate, 2xNAD, 2xCoA
- OUT: 2x Acetyl CoA, 2x NADH, 2xCO2
- Krebs Cycle
- 1. Acetyl CoA combines with oxaloacetate to form citrate
- CoA picks up another acetyl group from link reaction
- Citrate is decarboxylated and dehydrogenated
- CO2 is released, NADH formed
- a-ketogluterateis formed
- further decarboxylation and dehyrogenation releasing CO2 - NADH
- ATP is formed
- Succinate is formed
- dehyrogenation converts to fumarate and reduces FAD
- Fumarate converted to malate, dehydrogenated to oxaloacetate - NADH
- dehyrogenation converts to fumarate and reduces FAD
- Succinate is formed
- ATP is formed
- further decarboxylation and dehyrogenation releasing CO2 - NADH
- a-ketogluterateis formed
- CO2 is released, NADH formed
- Citrate is decarboxylated and dehydrogenated
- CoA picks up another acetyl group from link reaction
- 2 ATP, 4CO2, 2FADH, 6NADH
- x2 for 1 glucose
- 1. Acetyl CoA combines with oxaloacetate to form citrate
- Electron Transport Chain
- NADH and FADh release H
- Hydrogen splits into proton and electrons
- Electrons move down ETC, energy is lost
- Energy pumps protons into mitochondrial matrix from intermembrane space
- Protons move down conc gradient via ATP synthase
- Energy combines ADP and Pi - chemiosmosis
- O2 accepts electron and combines with proton - h2o
- Energy combines ADP and Pi - chemiosmosis
- Protons move down conc gradient via ATP synthase
- Energy pumps protons into mitochondrial matrix from intermembrane space
- Electrons move down ETC, energy is lost
- Hydrogen splits into proton and electrons
- NADH and FADh release H
- Glycolysis
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