Regulation of insulin levels in the blood

Regulation of insulin levels in the blood

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  • Created by: Ruby
  • Created on: 18-11-12 23:58
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  • Regulation of insulin levels in the blood
    • 1. The cell membrane of the beta contain both calcioum channels and potassium channels
      • 2.The potassium cahnnels are normally open /Ca normally closed. So K ions diffuse from the inside of the cell, makes inside -ve. At resting potential,the cell membrane is -tomV
  • 3.When glucose concentration ouside the cell iis high, glucose molecule CAN diffuse into the cell
    • 2.The potassium cahnnels are normally open /Ca normally closed. So K ions diffuse from the inside of the cell, makes inside -ve. At resting potential,the cell membrane is -tomV
    • 4. Glucose ienters the cell, is phosphorylates by glucose kinase. Glucose is quickly used in metabolism to produce ATP
      • 5. Extra ATP Causes the K channels to close, since K are senstitve to the amount of ATP in the cell
        • 6. kIONS ARE NO LONGER ABLE TO DIFFUSE OUT, ACTING AS A POTENTIial difference arouss the cell membrane. Becomes less -ve than the outside
          • 8. This changes the potential difference, opens the Calcium ions channels
            • 9. Calcium flood into the cell from the tissue, causes the secretion  of insulin by makiing the vesicles containing insulin move to the plasma membrane, fuse with the plasma membrane releasing inslin via exocytiosis
              • 1. The cell membrane of the beta contain both calcioum channels and potassium channels
    • 6. kIONS ARE NO LONGER ABLE TO DIFFUSE OUT, ACTING AS A POTENTIial difference arouss the cell membrane. Becomes less -ve than the outside
      • 8. This changes the potential difference, opens the Calcium ions channels
        • 9. Calcium flood into the cell from the tissue, causes the secretion  of insulin by makiing the vesicles containing insulin move to the plasma membrane, fuse with the plasma membrane releasing inslin via exocytiosis

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