Red Blood Cells
- Created by: DHorwood
- Created on: 20-10-14 11:29
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- Red Blood Cells
- bi concave discs
- no nucleus
- produced in red bone marrow
- lifespan 7 months /7 day life
- exchange of gases 02 and C02
- flexible for transport to smaller vessels
- contain red pigment (haemoglobin rich in iron
- broken down in spleen, bone marrow and liver
- iron retained for new haemoglobin formation
- normal hameoglobin count in men is 13-18gm per 100ml
- blood grouping determined by presence of antigens from inherited characteristics, the body makes antibodies to these antigens.
- Blood grouping
- Rhesus factor refers to specific antigen either - or + 85% + and 15% - but can be made in pregnancy
- blood groups A, B, AB, O
- Blood grouping
- Haemoglobin
- large globular protein called Globin with pigmented iron complex called Haem
- each molecule consists of 4 globin chains, four haem units and one iron atom attached to each
- iron atom combines with oxygen, so each haemoglobin molecule carries 4 oxygen molecules
- 280 million HG in each red blood cell
- Oxyhaemoglobin is when all iron sites are full/saturated with O2
- increase O2 makes blood bright red, low oxygen in blood turns blue
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