Red Blood Cells

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  • Created by: DHorwood
  • Created on: 20-10-14 11:29
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  • Red Blood Cells
    • bi concave discs
    • no nucleus
    • produced in red bone marrow
    • lifespan 7 months /7 day life
    • exchange of gases 02 and C02
    • flexible for transport to smaller vessels
    • contain red pigment (haemoglobin rich in iron
    • broken down in spleen, bone marrow and liver
    • iron retained for new haemoglobin formation
    • normal hameoglobin count in men is 13-18gm per 100ml
  • blood grouping determined by presence of antigens from inherited characteristics, the body makes antibodies to these antigens.
    • Blood grouping
      • Rhesus factor refers to specific antigen either - or + 85% + and 15% - but can be made in pregnancy
      • blood groups A, B, AB, O
  • Haemoglobin
    • large globular protein called Globin with pigmented iron complex called Haem
    • each molecule consists of 4 globin chains, four haem units and one iron atom attached to each
    • iron atom combines with oxygen, so each haemoglobin molecule carries 4 oxygen molecules
    • 280 million HG in each red blood cell
    • Oxyhaemoglobin is when all iron sites are full/saturated with O2
    • increase O2 makes blood bright red, low oxygen in blood turns blue

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