Protein topics
- Created by: allardyced
- Created on: 03-04-18 15:15
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- Proteins
- Amino acid biosynthesis
- Nitrogen fixation
- Haber process
- N2 + 3H2 ---> 2NH3
- Lightning
- Split N2, react with O2
- N fixing bacteria / algae
- Nitrogenase complex
- reduction
- Nitrogenase complex
- Haber process
- Assimilation
- a-ketoglutarate
- glutamate
- glutamine
- Glutamate synthetase. ATP
- glutamine
- glutamate dehydrogenase. NADH
- glutamate
- Glutamate synthetase. ATP
- Glutamate synthetase. ATP
- glutamate
- glutamate
- a-ketoglutarate
- Transamination
- Carbon skeletons
- keto-acids
- aminotransferases
- Pyridoxal phosphate (PLP)
- aminotransferases
- Major metabolic precursors
- Further reactions: oxidation, hydrolysis, methylation
- S-adenosylmethionine (SAM)
- Further reactions: oxidation, hydrolysis, methylation
- keto-acids
- Carbon skeletons
- Nitrogen fixation
- Protein synthesis
- Elongation
- EF1a carries tRNA to (A) aminoacyl site
- Peptide bond formation at Peptidyl transferase centre (P)
- Translocation to move in triplet code
- Peptide bond formation at Peptidyl transferase centre (P)
- EF1a carries tRNA to (A) aminoacyl site
- Termination
- eRF1 release factor binds at stop codon
- Cleaves polypeptide chain
- eRF1 release factor binds at stop codon
- Post-translational modifications
- Phosphorylation, methylation, acetylation, hydroxylation
- Enhances complexity
- Phosphorylation, methylation, acetylation, hydroxylation
- Elongation
- Amino acid catabolism
- Transamination
- Glutamate
- Oxidative deamination
- NH4+
- a-ketoglutarate
- Oxidative deamination
- Glutamate
- Urea cycle
- remove excess N
- 5 step cycle
- Transamination
- Protein degradation
- Digestive system
- Zymogens
- Active enzyme proteases
- acidic pH
- Zymogens
- Active enzyme proteases
- Zymogens
- Zymogens
- Non-specific proteases
- Serine protease activity
- Ser-His-asp catalytic triad
- Lysosomal proteolysis
- hydrolytic enzymes
- non-selective
- Serine protease activity
- Ubiquitin-proteasome pathway
- Ubiquitination
- E1 activation
- E2 conjugation
- E3 - ligation
- 19S cap
- Recognition
- Unfolding
- 20S core
- B1, B2, B5
- Threonine protease mechanism
- Catalytic centre
- Threonine protease mechanism
- Catalytic centre
- B1, B2, B5
- Ubiquitination
- Digestive system
- Amino acid biosynthesis
- eIF2 + GTP activate tRNA
- Initiation
- Protein synthesis
- Elongation
- EF1a carries tRNA to (A) aminoacyl site
- Peptide bond formation at Peptidyl transferase centre (P)
- Translocation to move in triplet code
- Peptide bond formation at Peptidyl transferase centre (P)
- EF1a carries tRNA to (A) aminoacyl site
- Termination
- eRF1 release factor binds at stop codon
- Cleaves polypeptide chain
- eRF1 release factor binds at stop codon
- Post-translational modifications
- Phosphorylation, methylation, acetylation, hydroxylation
- Enhances complexity
- Phosphorylation, methylation, acetylation, hydroxylation
- Elongation
- eIF1 & 3 bind 40s
- PIC scans for start AUG
- eIF2 + GTP activate tRNA
- Initiation
- eIF1 & 3 bind 40s
- PIC scans for start AUG
- PIC scans for start AUG
- eIF4 binds 5' cap
- eIF1 & 3 bind 40s
- Initiation
- eIF2 + GTP activate tRNA
- PIC scans for start AUG
- eIF4 binds 5' cap
- Protein synthesis
- Initiation
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