Process of Infection
- Created by: Chlo8
- Created on: 13-03-22 13:56
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- Process of Infection
- Colonization
- Infectious microorganisms exist in reservoirs
- Transmitted via direct contact, direct exposure or indirectly through vectors
- Human-to-human transmission by aerosolized microorganisms in droplets
- After deposit in receptive environment - microorganism stabilises adherence to the tissue through specific surface receptors
- Human-to-human transmission by aerosolized microorganisms in droplets
- Transmitted via direct contact, direct exposure or indirectly through vectors
- Infectious microorganisms exist in reservoirs
- Invasion
- Infectious agent can invade surrounding tissue/ other sites
- Developed mechanisms to penetrate tissues and avoid host's nonspecific and specific defences
- Infectious agent can invade surrounding tissue/ other sites
- Multiplication
- Warm, nutrient filled host environment
- Undergo rapid multiplication - replicate within infected cells; replicate in microphages and other cells.
- Warm, nutrient filled host environment
- Spread
- Produce localised infections without spread to other regions of the body
- Others highly invasive - may enter lymphatics, blood, internal organs.
- Successful spread - relies on virulence factors - adhesion molecules, toxins and protection against host's inflammatory and immune system
- If host has: Intact immune system- microorganism remains localised. Immune or inflammatory system compromised - infection may rapidly spread.
- Successful spread - relies on virulence factors - adhesion molecules, toxins and protection against host's inflammatory and immune system
- Others highly invasive - may enter lymphatics, blood, internal organs.
- Produce localised infections without spread to other regions of the body
- Colonization
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