Pregnancy Anaesthesia considerations
- Created by: Caroline Malik
- Created on: 19-11-19 17:22
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- Pregnancy
- Risks
- First trimester - embryo toxicity
- Second trimester - placental separation
- Third trimester - major physiological changes
- CV changes
- CO and blood volume increase
- both plasma volume & red cell mass increase
- albumin levels decrease
- cardiac reserve decreases nb animals with pre existing cardiac disease
- SVR decreases
- Hypotension
- Respiratory changes
- Minute voulme & O2 consumption increases
- FRC decreased
- GI changes
- Gravid uterus places pressure on stomach
- oesophagus kinked by altered position
- increase serum progesterone
- more prone to regurgitation
- Renal effects
- RBF & GFR increase
- urea and creatinine concentrations decrease
- Anaesthesia
- Premed
- dam often exhausted
- premed passed to offspring
- pethidine IM
- premed passed to offspring
- dam often exhausted
- Maintenance
- low resistance breathing system
- may need to IPPV
- use of N2O is controversial
- NMBs will not cross the placenta
- use of N2O is controversial
- may need to IPPV
- low resistance breathing system
- Positioning
- gravid uterus will put pressure on the aorta and vena cava which will reduce venous return and CO
- vena cava is the easiest to compress and lies to the right of midline, so tilt animal to the left
- gravid uterus will put pressure on the aorta and vena cava which will reduce venous return and CO
- Premed
- Risks
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