Metabolic Responses to Stress

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  • Created by: Nathan
  • Created on: 18-04-13 16:08
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  • Physiological Stress on Metabolism
    • Physiological stresses
      • Burns
      • Surgery
      • Trauma
      • Fever
      • Infections
    • Metabolic Responses to Stress
      • Inc. caloric intake
        • Often unable to meet nutritional demands
      • Inc. risk of infection
        • Suppressed immune system
      • Rise in metabolic rate
        • Body need more energy
      • Impaired liver, kidney & heart funtion
      • Endogenous resources used for repair & healing
        • Proteolysis of lean body mass
      • Losses of vitamins, minerals and electrolyes
    • Endocrine Responses
      • Cortisol utilises AAs from skeletal protein
      • Adrenaline  stimulates glycogenolysis, lypolysis and gluconeogenesis
      • Aldosterone- sodium retention
      • ADH- water retention
        • Maintains blood volume
          • Adrenaline  stimulates glycogenolysis, lypolysis and gluconeogenesis
      • Interleukin-1&6 and tissue necrosis factor
        • Produced by phagocytes in response to tissue damage
        • Induce production of proteins

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