Phagocytosis

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  • Created by: emily.tx
  • Created on: 03-05-17 12:05
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  • Pathogens produce chemicals which attract phagocytes
    • Phagocyte- specialised white blood cell that engulf and destroy pathogens
    • Stage 1
    • Phagocytes recognise non-human proteins on a pathogen
      • This is a response to a cell or organism that is non-self (not to a specific type of pathogen)
      • Stage 2
      • The phagocyte engulfs the pathogen where it is enclosed in the vacuole
        • This is called a Phagosome
        • Stage 3
        • The phagosome combines with a lysosome to form a phagolysosome
          • A lysosome is a specialised vesicle that contains hydrolytic enzymes for the breakdown of waste in a cell
          • Stage 4
          • Enzymes from the lysosome digest and destroy the pathogen
            • Stage 5
            • The digested pathogen absorbed by phagocyte antigens combine with the MHC in the cytoplasm
              • MHC- Major histocompatibility complex
              • Stage 6
              • MHC/antigen is displayed on the phagocyte membrane to make an APC
                • APC- Antigen presenting cell
                • Stage 7
  • Phagocytes recognise non-human proteins on a pathogen
    • This is a response to a cell or organism that is non-self (not to a specific type of pathogen)
    • Stage 2
    • The phagocyte engulfs the pathogen where it is enclosed in the vacuole
      • This is called a Phagosome
      • Stage 3
      • The phagosome combines with a lysosome to form a phagolysosome
        • A lysosome is a specialised vesicle that contains hydrolytic enzymes for the breakdown of waste in a cell
        • Stage 4
        • Enzymes from the lysosome digest and destroy the pathogen
          • Stage 5
          • The digested pathogen absorbed by phagocyte antigens combine with the MHC in the cytoplasm
            • MHC- Major histocompatibility complex
            • Stage 6
            • MHC/antigen is displayed on the phagocyte membrane to make an APC
              • APC- Antigen presenting cell
              • Stage 7
  • A key process in the non-specific and specific defencesyste,
    • Phagocytosis
      • Pathogens produce chemicals which attract phagocytes
        • Phagocyte- specialised white blood cell that engulf and destroy pathogens
        • Stage 1

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