Parkinson's disease management algorithm
- Created by: MazzaW
- Created on: 07-12-19 15:24
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- Newly diagnosed PD
- Biologically frail, comorbidities, cognitive impairment
- L-DOPA therapy
- MAOI, COMT inhibitor
- Dyskinesias: decrease L-DOPA dose, add amantadine
- Severe motor fluctuations despite optimal oral therapy: SC Apo or DuoDopa
- Severe resistant tremor or severe motor fluctuations: DBS
- MAOI, COMT inhibitor
- L-DOPA therapy
- Young onset, biologically fit, minimal comorbidities, mild Sx
- MAOI or DA
- L-DOPA therapy, COMT inhibitor
- Dyskinesias: decrease L-DOPA dose, add amantadine
- Severe motor fluctuations despite optimal oral therapy: SC Apo or DuoDopa
- Severe resistant tremor or severe motor fluctuations: DBS
- L-DOPA therapy, COMT inhibitor
- MAOI or DA
- Biologically frail, comorbidities, cognitive impairment
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