Non-specific respose to infection
- Created by: Eva
- Created on: 10-01-13 13:42
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- Non-specific response to infection
- Recognises the difference between self and non-self
- Reacts against anything non-self
- Inflammation
- Locaised infection
- The damaged cells release histamines
- Cause blood vessels to dialate causing heat and redness
- Higher temp reduces effectiveness of pathogen reproduction
- Cause walls of capillaries to seperate so fluid leaks in
- Plasma, WBCs and antibodies go to area
- Cause blood vessels to dialate causing heat and redness
- RASH: wide spread form of inflammation due to tissue damage
- Fever
- Hypothelamus maintains body temp
- Raised body temp reduces pathogen growth and reproductions
- Specific response more effective at higher temps
- Negative: above 40oC can lead to denaturation - tissue damage. Loss of water & electrolytes - dehydration
- Phagocytosis
- Granulocytes and Agranulocytes engulf and digest pathogens or non-self material
- Neutrophils (mainly G)
- Pus: build up of dead neutrophils
- Macrophages (mainly A)
- Produce antibodies
- Neutrophils (mainly G)
- Inflammation
- Locaised infection
- The damaged cells release histamines
- Cause blood vessels to dialate causing heat and redness
- Higher temp reduces effectiveness of pathogen reproduction
- Cause walls of capillaries to seperate so fluid leaks in
- Plasma, WBCs and antibodies go to area
- Cause blood vessels to dialate causing heat and redness
- RASH: wide spread form of inflammation due to tissue damage
- Granulocytes and Agranulocytes engulf and digest pathogens or non-self material
- Lyzosyme: destroys cell walls in bodily fluids
- Interferons
- Produced when as cell is invaded by a virus
- Viral-replication-inhibitary proteins
- Diffuses into other cells and binds to receptors on surface memberanes
- Helps prevent viral reproduction in cells to limit infection of more cells
- Recognises the difference between self and non-self
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