non-specific immunity
- Created by: Emilyburkee
- Created on: 20-04-21 11:44
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- Non-specific immunity
- role of antigens
- non-self antigens induce an immune response as they allow the immune cells to recognise foreign cells
- is a chemical which can produce an immune response
- normally proteins
- phagocytosis
- tye phagocyte follows chemical trail- chemotaxes left by the pathogen
- recognises antigens
- engulfs the pathogen, forming a phagosome around it
- once in the cell, lysosomes fuse with the phagosome and releases hydrolytic emzymes
- pathogen is digested and any indigestible substances ejected via exocytosis
- antigens of pathogen can be displayed on cell surface
- tye phagocyte follows chemical trail- chemotaxes left by the pathogen
- HIV
- is a retro virus
- damages white blood cells (Th cell) cant coordinate immune response
- Binds to CD4 on Th cell membrane and injects contents
- travels to the nucleus and reverse transcriptase converts RNA to DNA
- intergrase incorporates dna inot host
- mRNA is transcribed for viral DNA and viral proteins are produced
- is a retro virus
- role of antigens
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