Neural explanations of OCD

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  • Neural explanations for OCD
    • The pre frontal cortex is overactive in people with OCD. The PFC is responsible for decision making and primitive aspects of behaviour
      • In people without OCD, the PFC becomes less active after certain behaviours e.g. getting rid of germs by washing hands
        • Over-activity means the obsession with washing hands continues in people with OCD so they keep washing their hands when they don't need to
    • Info on SERT and COMT genes are relevant also.
    • Salloway and Duffy did brain scans on people with OCD and found increased activity in PFC
    • Cause and effect is difficult to establish with neurotransmitters.


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