Cell Division

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  • Cell Division
    • Interphase
      • The longest part of the cell cycle. The cell spends 90% of its time here.
      • DNA is doubled during this period. Just before the next cell division the chromosomes replicate so that each consists of 2 chromatids joined together by the centromere.
      • Mitosis uses considerable metabolic activity so a lot of ATP is generated in this stage.
      • The Chromosomes are not visible at interphase because the chromatin is dispersed throughout the nucleus.
    • Prophase
      • The chromosomes condense and become visible.
      • The centrioles migrate to the opposite ends of the cell.
      • Protein microtubules form from each centriole and the spindle develops, extending from pole-to-pole.
      • Towards the end of prophase the nuclear membrane disintegrates and the nucleolus disappears.
      • Pairs of chromatids can clearly be seen lying free in the cytoplasm.
    • Metaphase
      • Chromosomes arrange themselves at the equator.
      • Chromosomes attach to the spindle at the centromere
    • Anaphase
      • This is a very rapid stage.
      • The centromere splits and the spindle fibres contract and pull the now separated chromatids to the poles, centromere first.
    • Telophase
      • The final stage of mitosis.
      • The chromosomes have now reached the poles of the cell and are referred to as chromosomes again.
      • They uncoil and lengthen.
      • The spindle breaks down, the nucleus reappears and the nuclear membrane reforms.
    • Cytokinesis
      • Cell division is completed by the separation of the cytoplasm between the two new nuclei.

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