Metabolism

  • Created by: SamDavies
  • Created on: 11-01-19 23:07
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  • Metabolism
    • Phase I
      • Oxidation
        • Hydroxylation
        • N- or S- oxidation
        • N-, O-, or S- delakylation
      • Reduction
        • Carbonyl to alcohol
        • Nitro to hydroxylamine or amine
      • Hydrolysis
        • Ester, amide or phosphate to corresponding alcohol, acid or amine
        • Hydrazides to acid and substituted hydrazine
    • Phase II
      • Glucuronidation
        • Carboxylic acids
        • Phenols
        • Alcohols
        • Amines
      • Sulfation
        • Alcohols
        • Phenols
        • Amines
      • Gultathione (GSH) conjugation
        • Halo-cpds
        • Epoxides
        • Arene oxides
        • Quinone-imines

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