Lymphocytes

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  • Lymphocytes
    • Natural Killer (NK) cells
      • do not have T or B cell receptors
      • Antibody independent
      • Antibody-dependant cell-mediated cytotoxicity (ADCC)
        • Cause lysis of the target cell
        • Recognise bound antibodies
      • Innate immune system
      • Mature in bone marrow
    • B Cells
      • Adaptive immune response
        • T cells
          • Cytotoxic T Cells
            • kill other cells
            • MHC class I restricted
            • CD8 T cells
          • Helper T Cells
            • CD4 T cells
            • Stimulate or help B Cells
              • Antibody-secreting cells
          • Regulatory T Cells
            • CD4 T cells
          • antigen specific
            • B Cells
              • Adaptive immune response
                • T cells
                  • Cytotoxic T Cells
                    • kill other cells
                    • MHC class I restricted
                    • CD8 T cells
                  • Helper T Cells
                    • Stimulate or help B Cells
                      • Antibody-secreting cells
                  • Regulatory T Cells
                    • antigen specific
                      • Cell mediated
                        • Develop in the bone marrow
                        • Mature in the thymus
                        • T cell receptor (TCR)
                          • Disulphide linked heterodimer
                    • Produces antibodies
                    • Develop and mature in the bone marrow
                    • B cell receptor (BCR)
                    • Differentiation
                      • Plasma Cells
                        • Memory Cells
                          • Immunological memory
                  • Cell mediated
                    • Develop in the bone marrow
                    • Mature in the thymus
                    • T cell receptor (TCR)
                      • Disulphide linked heterodimer
                • Produces antibodies
                • Develop and mature in the bone marrow
                • B cell receptor (BCR)
                • Differentiation
                  • Plasma Cells
                    • Memory Cells
                      • Immunological memory

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