Lustman - Non-adherence - Fluoxetine (depression).
- Created by: Steff06
- Created on: 01-04-16 11:43
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- Lustman
- Aim:
- To assess the EFFICACY of the anti-depressant FLUOXETINE in treating DEPRESSION by measuring GLYCEMIC control.
- Methodology:
- Randomised, control DOUBLE-BLIND study.
- Participants:
- 60 participants with DIABETES, 26 had TYPE 1 diabetes, 34 had TYPE 2 diabetes.
- Procedure:
- Patients RANDOMLY assigned to either FLUOXETINE or PLACEBO group. Study conducted over 8 WEEKS. Patients assessed for depression using PSYCHOMETRIC tests and their ADHERENCE to their medical regimen was measured by measuring their GHb.
- Findings:
- Patients using Fluoxetine reported LOWER levels of depression. They also had LOWER levels of GHb, which indicated their IMPROVED adherence.
- Conclusion:
- Measuring GHb in patients with diabetes indicates their LEVEL of adherence to prescribed medical regimes.
- Greater adherence was shown by patients who were LESS depressed.
- Aim:
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